SCHEMBL23933309

SCHEMBL23933309

CCOC(C=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)OCC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
PPARA Q07869 2/20 0.44
IDO1 P14902 3/20 0.34
PTGS1 P23219 1/20 0.34
TDO2 P48775 1/20 0.34
TACR1 P25103 2/20 0.33
NFE2L2 Q16236 1/20 0.32
AHR P35869 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
MAOB P27338 1/20 0.31
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23933308 1.00 PPARG (0.44) PPARGPPARDPPARAIDO1PTGS1
SCHEMBL23961562 0.91 PPARG (0.38) PPARGPPARDPPARAPTGS1NFE2L2
SCHEMBL27168887 0.78 PTGS1 (0.35) PPARGPPARDPPARAIDO1PTGS1
SCHEMBL27168889 0.78 PTGS1 (0.35) PPARGPPARDPPARAIDO1PTGS1
SCHEMBL9967782 0.74 NFE2L2 (0.37) PPARGPPARDPPARAIDO1PTGS1
SCHEMBL30138657 0.74 APP (0.35) NFE2L2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL21996054 0.74 APP (0.35) NFE2L2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL21996056 0.74 APP (0.35) NFE2L2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL18143788 0.74 AHR (0.41) AHR
SCHEMBL18143790 0.74 AHR (0.41) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4334275-A1 HALOCYCLOPROPANATION PROCESSES Corteva Agriscience LLC (US) 2024-03-13 EP claimed
EP-4334275-B1 HALOCYCLOPROPANATION PROCESSES CORTEVA AGRISCIENCE LLC (US) 2026-01-21 EP disclosed
EP-4334275-A1 HALOCYCLOPROPANATION PROCESSES Corteva Agriscience LLC (US) 2024-03-13 EP disclosed
US-20230220427-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2023-07-13 US disclosed
EP-4139272-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS Corteva Agriscience LLC (US) 2023-03-01 EP disclosed
WO-2022235863-A1 HALOCYCLOPROPANATION PROCESSES CORTEVA AGRISCIENCE LLC (US) 2022-11-10 WO disclosed
WO-2021216629-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS CORTEVA AGRISCIENCE LLC (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220427-A1 PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS DDT, PCCA, DDC PPARG 584/4885PPARD 586/4885PPARA 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.