Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993526 | 0.80 | CYP11B1 (0.48) | CYP11B1CYP11B2KCNN4TSHRALDH1A1 | |
| SCHEMBL5479925 | 0.79 | CYP19A1 (0.66) | CYP11B1CYP11B2KCNN4TSHRALOX15 | |
| SCHEMBL30577371 | 0.74 | CYP11B1 (0.57) | CYP11B1CYP11B2KCNN4TSHRALDH1A1 | |
| SCHEMBL14590840 | 0.72 | CYP11B1 (0.46) | CYP11B1CYP11B2KCNN4TSHRALDH1A1 | |
| SCHEMBL332630 | 0.72 | CYP11B1 (1.00) | CYP11B1CYP11B2KCNN4TSHRALOX15 | |
| SCHEMBL31298430 | 0.69 | CYP11B1 (0.67) | CYP11B1CYP11B2KCNN4TSHRALOX15 | |
| SCHEMBL9650536 | 0.67 | CYP2B6 (0.46) | CYP11B1CYP11B2KCNN4TSHRALDH1A1 | |
| SCHEMBL2392136 | 0.63 | CYP2B6 (0.59) | CYP11B1CYP11B2KCNN4TSHRALDH1A1 | |
| SCHEMBL1108511 | 0.63 | TSHR (0.65) | KCNN4TSHRALDH1A1ALOX15MAPK1 | |
| SCHEMBL30068584 | 0.62 | KDM4E (0.44) | CYP11B1CYP11B2KCNN4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| WO-2017070536-A1 | METHODS AND AGENTS FOR TREATING DISEASES | ANGION BIOMEDICA CORP. (US) | 2017-04-27 | — | — | WO | disclosed |
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090048270-A1 | Compounds, Methods And Devices for Inhibiting Neoproliferative Changes in Blood Vessel Walls | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-02-19 | — | — | US | disclosed |
| US-20070293554-A1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-12-20 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |
| US-6803375-B1 | IMMUNOMODULATION IN A MAMMALIAN PATIENT WITHOUT CAUSING SUBSTANTIAL INHIBITION OF CYTOCHROME P-450 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-10-12 | — | — | US | disclosed |
| EP-0093925-A1 | Azolyl butynes, process for their preparation and their use as fungicides and plant growth regulators | BAYER AG (DE) | 1983-11-16 | — | — | EP | disclosed |
| US-4243670-A | MICROBORICIDES; FUNGICIDES; SPORICIDES; HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4073901-A | Metal complexes of N-trityl-azoles for combatting fungi | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
| US-4073901-A | Metal complexes of N-trityl-azoles for combatting fungi | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
| US-4073901-A | Metal complexes of N-trityl-azoles for combatting fungi | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048270-A1 | Compounds, Methods And Devices for Inhibiting Neoproliferative Changes in Blood Vessel Walls | PGF, VEGFA, MKI67 | CYP11B1 3035/4885CYP11B2 3681/4885KCNN4 4235/4885 |
| US-20070293554-A1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | NFATC1, ORAI1, KCNMA1 | CYP11B1 291/4885CYP11B2 653/4885KCNN4 10/4885 |
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | MC1R, TYR, NAMPT | CYP11B1 845/4885CYP11B2 1675/4885KCNN4 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.