Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393355 | 0.80 | CYP11B1 (0.56) | CYP11B1CYP11B2KCNN4TSHRSMN1; SMN2 | |
| SCHEMBL14590840 | 0.70 | CYP11B1 (0.46) | CYP11B1CYP11B2KCNN4TSHRSMN1; SMN2 | |
| SCHEMBL30577371 | 0.67 | CYP11B1 (0.57) | CYP11B1CYP11B2KCNN4TSHRSMN1; SMN2 | |
| SCHEMBL10548625 | 0.65 | KMT2A (0.34) | KMT2A | |
| SCHEMBL332630 | 0.65 | CYP11B1 (1.00) | CYP11B1CYP11B2KCNN4TSHRSMN1; SMN2 | |
| SCHEMBL6368612 | 0.65 | MGLL (0.44) | CYP11B1CYP11B2KCNN4TSHRHTT | |
| SCHEMBL316824 | 0.64 | — | — | |
| SCHEMBL16001319 | 0.64 | LMNA (0.44) | TSHRSMN1; SMN2CA2MAPTKMT2A | |
| SCHEMBL2490844 | 0.64 | PARL (0.41) | CYP11B1CYP11B2KCNN4TSHRSMN1; SMN2 | |
| SCHEMBL7319404 | 0.64 | KMT2A (0.52) | SMN1; SMN2ADORA2AADORA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |