Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933911 | 1.00 | TAAR1 (0.47) | TAAR1IDO1AGXTALDH1A1HTT | |
| SCHEMBL23933910 | 1.00 | TAAR1 (0.47) | TAAR1IDO1AGXTALDH1A1HTT | |
| SCHEMBL23933764 | 0.89 | MTNR1A (0.46) | TAAR1IDO1AGXTALDH1A1HTT | |
| SCHEMBL23933766 | 0.89 | MTNR1A (0.46) | TAAR1IDO1AGXTALDH1A1HTT | |
| SCHEMBL23933760 | 0.89 | MTNR1A (0.46) | TAAR1IDO1AGXTALDH1A1HTT | |
| SCHEMBL23933796 | 0.86 | PNMT (0.43) | IDO1AGXTCNR1 | |
| SCHEMBL23933798 | 0.86 | PNMT (0.43) | IDO1AGXTCNR1 | |
| SCHEMBL23933793 | 0.86 | PNMT (0.43) | IDO1AGXTCNR1 | |
| SCHEMBL23933767 | 0.85 | SRR (0.50) | — | |
| SCHEMBL23933769 | 0.85 | SRR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |