Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CCR6 | P51684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933954 | 0.81 | RAPGEF4 (0.58) | RAPGEF4LMNA | |
| SCHEMBL23868374 | 0.78 | RAPGEF4 (0.39) | RAPGEF4 | |
| SCHEMBL23453351 | 0.74 | CXCR2 (0.46) | RAPGEF4EPHX2CXCR2CTSCCCR6 | |
| SCHEMBL18719382 | 0.74 | HDAC1 (0.51) | CXCR2CCR6 | |
| SCHEMBL18719383 | 0.74 | HDAC1 (0.51) | CXCR2CCR6 | |
| SCHEMBL14384621 | 0.74 | HDAC1 (0.51) | CXCR2CCR6 | |
| SCHEMBL23453400 | 0.74 | MAPT (0.50) | CXCR2CCR6LMNA | |
| SCHEMBL23453350 | 0.72 | EPHX1 (0.49) | EPHX2CXCR2CNR1CNR2CCR6 | |
| SCHEMBL24787390 | 0.72 | CXCR2 (0.51) | EPHX2CXCR2ARCCR6 | |
| SCHEMBL17427558 | 0.72 | FFAR1 (0.42) | RAPGEF4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324141-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | HENKEL AG & CO. KGAA (DE) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324141-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | UROD, IDH3A, SQLE | RAPGEF4 3592/4885EPHX2 3485/4885CXCR2 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.