Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23868374 | 0.74 | RAPGEF4 (0.39) | RAPGEF4POLB | |
| SCHEMBL3970619 | 0.73 | ALDH1A1 (0.72) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL23933952 | 0.72 | RAPGEF4 (0.45) | LMNARAPGEF4 | |
| SCHEMBL17423689 | 0.71 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL810836 | 0.69 | ALDH1A1 (0.64) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL23933954 | 0.68 | RAPGEF4 (0.58) | LMNARAPGEF4MAPT | |
| SCHEMBL8245793 | 0.68 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL1968485 | 0.67 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL15618828 | 0.66 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL15621853 | 0.66 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005407-A1 | ONE-POT SYNTHESIS OF SQUARAMIDES | UNIVERSIDAD DE ZARAGOZA (ES) | 2016-01-14 | — | — | WO | disclosed |