Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.58 |
| ▸ | XPO1 | O14980 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256134 | 0.88 | RAPGEF4 (0.51) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL17427531 | 0.88 | RAPGEF4 (0.51) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL15256111 | 0.87 | RAPGEF4 (0.50) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL15256120 | 0.87 | RAPGEF4 (0.50) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL15258515 | 0.87 | RAPGEF4 (0.59) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL17423676 | 0.85 | RAPGEF4 (0.49) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL15256125 | 0.82 | RAPGEF4 (0.50) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL23933952 | 0.81 | RAPGEF4 (0.45) | RAPGEF4LMNA | |
| SCHEMBL394467 | 0.81 | RAPGEF4 (0.59) | RAPGEF4XPO1AKR1C3AKR1C2MAPT | |
| SCHEMBL25106975 | 0.80 | KIF11 (0.48) | RAPGEF4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324141-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | HENKEL AG & CO. KGAA (DE) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324141-A1 | METHOD FOR PRODUCING NON-ISOCYANATE POLYURETHANES | UROD, IDH3A, SQLE | RAPGEF4 3592/4885XPO1 3725/4885AKR1C3 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.