Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934703 | 0.87 | THRB (0.35) | — | |
| SCHEMBL23934597 | 0.85 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL23739734 | 0.76 | NR1H2 (0.32) | NR1H2NR1H3 | |
| SCHEMBL23934500 | 0.75 | MEN1 (0.37) | — | |
| SCHEMBL23934416 | 0.73 | THRB (0.31) | — | |
| SCHEMBL19069020 | 0.71 | CRBN (0.38) | — | |
| SCHEMBL23934442 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL24830076 | 0.68 | MTNR1A (0.37) | NR1H2NR1H3 | |
| SCHEMBL24830149 | 0.68 | MTNR1A (0.32) | — | |
| SCHEMBL20631262 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896062-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-10-20 | — | — | EP | disclosed |