Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739482 | 0.83 | MTNR1A (0.34) | — | |
| SCHEMBL23739659 | 0.81 | — | — | |
| SCHEMBL23739470 | 0.81 | LMNA (0.36) | — | |
| SCHEMBL19069020 | 0.81 | CRBN (0.38) | — | |
| SCHEMBL20631262 | 0.79 | — | — | |
| SCHEMBL24830076 | 0.77 | MTNR1A (0.37) | NR1H2NR1H3 | |
| SCHEMBL23934712 | 0.76 | NR1H2 (0.32) | NR1H2NR1H3 | |
| SCHEMBL23739743 | 0.76 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL23740080 | 0.76 | HTR1A (0.48) | HTR2A | |
| SCHEMBL23739825 | 0.75 | HTR1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862348-A1 | ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |