SCHEMBL239348

SCHEMBL239348

O=C1C2C3C=CC(O3)C2C(=O)N1CCO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.50
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
HSD17B10 Q99714 2/20 0.46
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.46
ATM Q13315 2/20 0.44
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.40
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
HPGD P15428 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
MEN1 O00255 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13989231 1.00 ALDH1A1 (0.50) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL18127060 1.00 ALDH1A1 (0.50) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL12284086 1.00 ALDH1A1 (0.50) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL18539440 0.89 ALDH1A1 (0.60) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL12744298 0.89 ALDH1A1 (0.60) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL16210943 0.86 ALDH1A1 (0.53) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL28416943 0.84 ALDH1A1 (0.50) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL28419881 0.84 ALDH1A1 (0.55) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL12284562 0.83 ALDH1A1 (0.43) ALDH1A1MAPTHTTHSD17B10USP2
SCHEMBL18126828 0.83 ALDH1A1 (0.43) ALDH1A1MAPTHTTHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12195587-B2 Synthesis of a biocompatible, biodegradable, and tunable shape memory polymer triggered at body temperature SHAPE MEMORY POLYMERS INC (CA) 2025-01-14 US claimed
US-20230312820-A1 SYNTHESIS OF A BIOCOMPATIBLE, BIODEGRADABLE, AND TUNABLE SHAPE MEMORY POLYMER TRIGGERED AT BODY TEMPERATURE SHAPE MEMORY POLYMERS INC (CA) 2023-10-05 US claimed
WO-2025085489-A1 GSPT1-DEGRADING COMPOUNDS, ANTI-CD33 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-24 WO disclosed
US-12195587-B2 Synthesis of a biocompatible, biodegradable, and tunable shape memory polymer triggered at body temperature SHAPE MEMORY POLYMERS INC (CA) 2025-01-14 US disclosed
US-20240293585-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS KODIAK SCIENCES INC. 2024-09-05 US disclosed
WO-2024160696-A2 CURABLE COMPOSITION, 3D-PRINTED OBJECT FORMED THEREFROM AND PROCESS OF FORMING THE SAME BASF SE (DE) 2024-08-08 WO disclosed
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2024-06-20 US disclosed
US-11939428-B2 Polyimides FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-03-26 US disclosed
US-11819531-B2 Multifunctional zwitterionic polymer conjugates KODIAK SCIENCES INC. (US) 2023-11-21 US disclosed
EP-3659591-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2023-10-25 EP disclosed
US-20230312820-A1 SYNTHESIS OF A BIOCOMPATIBLE, BIODEGRADABLE, AND TUNABLE SHAPE MEMORY POLYMER TRIGGERED AT BODY TEMPERATURE SHAPE MEMORY POLYMERS INC (CA) 2023-10-05 US disclosed
WO-2011075736-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 WO disclosed
US-20100261841-A1 Intermediates Useful in the Preparation of Maleimide Functionalized Polymers NEKTAR THERAPEUTICS (US) 2010-10-14 US disclosed
US-20100261841-A1 Intermediates Useful in the Preparation of Maleimide Functionalized Polymers NEKTAR THERAPEUTICS (US) 2010-10-14 US disclosed
US-20100261841-A1 Intermediates Useful in the Preparation of Maleimide Functionalized Polymers NEKTAR THERAPEUTICS (US) 2010-10-14 US disclosed
US-7790835-B2 Water soluble, non-peptidic polymer covalently attached to a Diels-Alder bicyclic or tricyclic imide ring; chemical intermediates NEKTAR THERAPEUTICS (US) 2010-09-07 US disclosed
US-7790835-B2 Water soluble, non-peptidic polymer covalently attached to a Diels-Alder bicyclic or tricyclic imide ring; chemical intermediates NEKTAR THERAPEUTICS (US) 2010-09-07 US disclosed
US-7790835-B2 Water soluble, non-peptidic polymer covalently attached to a Diels-Alder bicyclic or tricyclic imide ring; chemical intermediates NEKTAR THERAPEUTICS (US) 2010-09-07 US disclosed
US-20080300348-A1 Polymer WARWICK EFFECT POLYMERS LIMITED 2008-12-04 US disclosed
US-20050176922-A1 Water soluble, non-peptidic polymer covalently attached to a Diels-Alder bicyclic or tricyclic imide ring; chemical intermediates NEKTAR THERAPEUTICS 2005-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293585-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS ACP1, PHOSPHO1, PARG ALDH1A1 4348/4885MAPT 2483/4885HTT 1801/4885
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 ALDH1A1 4195/4885MAPT 2256/4885HTT 2809/4885
US-11819531-B2 Multifunctional zwitterionic polymer conjugates PHOSPHO1, MSN, ZW10 ALDH1A1 4195/4885MAPT 2256/4885HTT 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.