SCHEMBL23934938

SCHEMBL23934938

CCC(C(N)=O)C(CC(C)c1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.49
TAAR1 Q96RJ0 2/20 0.42
ACE P12821 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
EPHX1 P07099 2/20 0.39
ALOX5 P09917 1/20 0.39
MME P08473 1/20 0.39
AOC3 Q16853 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017784 0.82 TRPA1 (0.49) TRPA1TAAR1TRPM8KMT2AEPHX1
SCHEMBL1716524 0.80 TRPA1 (0.53) TRPA1TAAR1MMEAOC3LMNA
SCHEMBL20182067 0.80 MEN1 (0.51) TRPA1KMT2AMEN1LMNA
SCHEMBL14033301 0.79 TRPA1 (0.53) TRPA1TAAR1TRPM8KMT2AMEN1
SCHEMBL12715042 0.78 TRPA1 (0.52) TRPA1TAAR1AOC3LMNA
SCHEMBL13948840 0.78 TRPA1 (0.52) TRPA1TAAR1AOC3LMNA
SCHEMBL13924945 0.78 TRPA1 (0.52) TRPA1TAAR1AOC3LMNA
SCHEMBL14601401 0.77 MMP1 (0.44) TRPA1TAAR1KMT2AMEN1ALOX5
SCHEMBL8446344 0.76 CYP1A2 (0.46) TRPM8KMT2AMEN1EPHX1ALOX5
SCHEMBL14601403 0.76 TRPA1 (0.46) TRPA1TAAR1KMT2AMEN1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896044-A1 MIXTURE FOR ENHANCING OPACITY Depco-Trh Pty Ltd (AU) 2021-10-20 EP disclosed