Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601403 | 0.81 | TRPA1 (0.46) | MEN1KMT2ALMNATRPA1 | |
| SCHEMBL23934938 | 0.80 | TRPA1 (0.49) | MEN1KMT2ALMNATRPA1 | |
| SCHEMBL12251346 | 0.79 | MEN1 (0.58) | MEN1KMT2ACRHBPCRHR2KLK7 | |
| SCHEMBL19433753 | 0.78 | MAPT (0.49) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL13921533 | 0.77 | MMP1 (0.51) | MEN1KMT2ALMNATRPA1 | |
| SCHEMBL13948388 | 0.77 | MMP1 (0.51) | MEN1KMT2ALMNATRPA1 | |
| SCHEMBL13948382 | 0.77 | MMP1 (0.51) | MEN1KMT2ALMNATRPA1 | |
| SCHEMBL24767431 | 0.76 | MEN1 (0.55) | MEN1KMT2ACRHBPCRHR2KLK7 | |
| SCHEMBL1716524 | 0.75 | TRPA1 (0.53) | LMNAMAPK1TRPA1 | |
| SCHEMBL13903927 | 0.74 | PKM (0.48) | MEN1KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094411-A1 | POLYMER RESINS WITH PHOSPHONATE OLIGOMERS | FRX POLYMERS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |