Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944058 | 0.93 | MDM4 (0.41) | MDM4TP53MDM2TLR2 | |
| SCHEMBL27256575 | 0.90 | MDM4 (0.42) | MDM4TP53MDM2BACE1CASP3 | |
| SCHEMBL29019482 | 0.85 | MDM4 (0.51) | MDM4TP53MDM2BACE1CASP3 | |
| SCHEMBL29019485 | 0.85 | MDM4 (0.51) | MDM4TP53MDM2BACE1CASP3 | |
| SCHEMBL30457847 | 0.85 | MDM4 (0.51) | MDM4TP53MDM2BACE1CASP3 | |
| SCHEMBL31370634 | 0.85 | MDM4 (0.51) | MDM4TP53MDM2BACE1CASP3 | |
| SCHEMBL10076575 | 0.82 | CASP3 (0.41) | MDM4TP53CASP3 | |
| SCHEMBL10022278 | 0.79 | MDM2 (0.52) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL24633696 | 0.78 | MDM4 (0.46) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL26761659 | 0.78 | MDM4 (0.38) | MDM4TP53MDM2CASP3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896056-A1 | AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-10-20 | — | — | EP | disclosed |