Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395894 | 1.00 | ALDH1A1 (0.39) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL30558752 | 0.76 | GPR84 (0.31) | GPR84 | |
| SCHEMBL30487691 | 0.76 | GAA (0.36) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL4895528 | 0.75 | ALDH1A1 (0.34) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL29008613 | 0.71 | P2RX4 (0.33) | — | |
| SCHEMBL5501970 | 0.71 | ALDH1A1 (0.34) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL17275723 | 0.65 | ALDH1A1 (0.50) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL297288 | 0.65 | GAA (0.41) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL30437327 | 0.65 | GAA (0.41) | ALDH1A1GAALMNAMCL1PAX8 | |
| SCHEMBL31414122 | 0.64 | GAA (0.39) | ALDH1A1GAALMNAMCL1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101768112-B | Two-photon induced luminous compound with symmetrical both ends and synthesis method and purposes thereof | CHINESE ACAD INST CHEMISTRY | 2012-05-30 | — | — | CN | disclosed |
| US-8017775-B2 | 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-13 | — | — | US | disclosed |
| CN-101768112-A | Two-photon induced luminous compound with symmetrical both ends and synthesis method and purposes thereof | CHINESE ACAD INST CHEMISTRY | 2010-07-07 | — | — | CN | disclosed |
| US-20090326009-A1 | Novel 1-2-Dihydroquinoline Derivative Having Glucocorticoid Receptor Binding Activity | Santen Pharmaceutical Co., (JP) | 2009-12-31 | — | — | US | disclosed |
| WO-2009103007-A2 | STEROID HORMONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-08-20 | — | — | WO | disclosed |
| US-4374958-A | WIRE OR CABLE WITH PROTECTIVE COATING, CROSSLINKING INHIBITION | UNION CARBIDE CORPORATION (US) | 1983-02-22 | — | — | US | disclosed |
| US-4046765-A | Dihydroquinoline derivatives of antioxidant activity and a process for the preparation thereof | MATERIAL KSZ. (HU) | 1977-09-06 | — | — | US | disclosed |
| US-4025631-A | Dihydroquinoline derivatives of antioxidant activity | MATERIAL KSZ. (HU) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326009-A1 | Novel 1-2-Dihydroquinoline Derivative Having Glucocorticoid Receptor Binding Activity | NR3C1, NR3C2, NR5A1 | ALDH1A1 3569/4885GAA 4651/4885LMNA 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.