SCHEMBL2393564

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9890675	0.86	SMN1; SMN2 (0.49)	PTGER2KDM4ESMN1; SMN2
	SCHEMBL2393626	0.86	RAB9A (0.46)	KDM4ESMN1; SMN2
	SCHEMBL9890781	0.81	TP53 (0.42)	PTGER2SMN1; SMN2
	SCHEMBL2392257	0.80	ICMT (0.54)	ICMTSLC9A1PARP1CHEK2HPGDS
	SCHEMBL6390159	0.78	MAPK8 (0.49)	TAAR1KDM4E
	SCHEMBL9890774	0.77	ICMT (0.54)	ICMTSLC9A1PARP1CHEK2HPGDS
	SCHEMBL9890764	0.77	ICMT (0.54)	ICMTSLC9A1PARP1CHEK2HPGDS
	SCHEMBL15782613	0.74	ICMT (0.55)	ICMTSLC9A1PARP1TAAR1
	SCHEMBL9890788	0.72	ICMT (0.50)	ICMTPTGER2SMN1; SMN2
	SCHEMBL9890780	0.72	ICMT (0.50)	ICMTCSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.