Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 5/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293770 | 0.92 | LIPE (0.36) | LIPEDGAT1ROCK2FFAR1AAK1 | |
| SCHEMBL20428054 | 0.89 | LIPE (0.35) | LIPEDGAT1ROCK2AAK1 | |
| SCHEMBL29879749 | 0.84 | LIPE (0.42) | LIPEAAK1SSTR4 | |
| SCHEMBL25300352 | 0.84 | LIPE (0.42) | LIPEAAK1SSTR4 | |
| SCHEMBL22293781 | 0.83 | LIPE (0.39) | LIPEDGAT1ROCK2FFAR1MEN1 | |
| SCHEMBL23935943 | 0.82 | LIPE (0.36) | LIPEROCK2 | |
| SCHEMBL29900384 | 0.80 | L3MBTL1 (0.36) | LIPE | |
| SCHEMBL365301 | 0.80 | L3MBTL1 (0.36) | LIPE | |
| SCHEMBL20428078 | 0.80 | LIPE (0.36) | LIPEDGAT1ROCK2 | |
| SCHEMBL20428063 | 0.78 | LIPE (0.35) | LIPEROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723808-B1 | COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES | H LUNDBECK AS (DK) | 2021-10-20 | — | — | EP | disclosed |