SCHEMBL23935943

SCHEMBL23935943

BC(B)(B)C(B)(O)Oc1ncccc1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 7/20 0.36
ROCK2 O75116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22293781 0.88 LIPE (0.39) LIPEROCK2
SCHEMBL20428063 0.86 LIPE (0.35) LIPEROCK2
SCHEMBL20428078 0.85 LIPE (0.36) LIPEROCK2
SCHEMBL29108916 0.82 LIPE (0.44) LIPEROCK2
SCHEMBL29760199 0.82 LIPE (0.44) LIPEROCK2
SCHEMBL22293770 0.82 LIPE (0.36) LIPEROCK2
SCHEMBL23935944 0.82 LIPE (0.36) LIPEROCK2
SCHEMBL20428054 0.78 LIPE (0.35) LIPEROCK2
SCHEMBL1484864 0.77 APLNR (0.38) LIPEROCK2
SCHEMBL30292561 0.77 APLNR (0.38) LIPEROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723808-B1 COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES H LUNDBECK AS (DK) 2021-10-20 EP disclosed