Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022758 | 0.84 | CA1 (0.40) | MAPTCA1CA2ALDH1A1KDM4E | |
| SCHEMBL6022750 | 0.84 | CA1 (0.40) | MAPTCA1CA2ALDH1A1KDM4E | |
| SCHEMBL13791030 | 0.82 | ALDH1A1 (0.48) | ESR1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL18538456 | 0.82 | ALDH1A1 (0.48) | ESR1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL18538454 | 0.82 | CYP1A1 (0.50) | ESR1MAPTCYP3A4DPP4TTR | |
| SCHEMBL2391253 | 0.80 | CYP3A4 (0.46) | ESR1CYP3A4DPP4TTREPAS1 | |
| SCHEMBL2391170 | 0.79 | FBP1 (0.46) | FBP1ESR1MAPTMEN1KMT2A | |
| SCHEMBL4009651 | 0.79 | ESR1 (0.52) | ESR1MAPTHSD17B1HSD17B2DPP4 | |
| SCHEMBL27537154 | 0.79 | KDM4E (0.52) | MAPTMEN1KMT2ACYP3A4DPP4 | |
| SCHEMBL2392289 | 0.79 | KDM4E (0.52) | MAPTMEN1KMT2ACYP3A4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |