Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23936729 | 0.84 | BCHE (0.68) | BCHEKDM2BGNAI3GNAO1GNAI1 | |
| SCHEMBL23936858 | 0.83 | GNAI3 (0.37) | GNAI3GNAO1GNAI1 | |
| SCHEMBL27454271 | 0.82 | BCHE (0.51) | BCHEKDM2BALDH1A1 | |
| SCHEMBL21214045 | 0.81 | BCHE (0.49) | BCHEKDM2BGNAI3GNAO1GNAI1 | |
| SCHEMBL12011335 | 0.80 | BCHE (0.65) | BCHEKDM2BGAAALDH1A1LMNA | |
| SCHEMBL23986334 | 0.72 | HSD17B10 (0.40) | BCHEHSD17B10ALDH1A1 | |
| SCHEMBL8402885 | 0.72 | BCHE (0.59) | BCHEKDM2B | |
| SCHEMBL14394 | 0.70 | LTA4H (0.43) | BCHECYP2D6TSHR | |
| SCHEMBL14250 | 0.70 | LTA4H (0.43) | BCHECYP2D6TSHR | |
| SCHEMBL13781 | 0.70 | LTA4H (0.43) | BCHECYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |