Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 7/20 | 0.63 |
| ▸ | VDR | P11473 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ST3GAL1 | Q11201 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575998 | 1.00 | ST6GAL1 (0.63) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL23923594 | 1.00 | ST6GAL1 (0.63) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL23923592 | 1.00 | ST6GAL1 (0.63) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL23923591 | 1.00 | ST6GAL1 (0.63) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL22855537 | 0.85 | ST6GAL1 (0.47) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL3695768 | 0.84 | VDR (0.68) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL3691830 | 0.84 | VDR (0.68) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL22871979 | 0.83 | VDR (0.82) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL20980004 | 0.83 | VDR (0.82) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 | |
| SCHEMBL7996253 | 0.83 | VDR (0.82) | ST6GAL1VDRCYP2C9HIF1AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323995-A1 | ISOLITHOCHOLIC ACID OR ISOALLOLITHOCHOLIC ACID AND DEUTERATED DERIVATIVES THEREOF FOR PREVENTING AND TREATING CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASES | PHENEX PHARMACEUTICALS AG (DE) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323995-A1 | ISOLITHOCHOLIC ACID OR ISOALLOLITHOCHOLIC ACID AND DEUTERATED DERIVATIVES THEREOF FOR PREVENTING AND TREATING CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASES | DHCR7, CYP27A1, SLC10A2 | ST6GAL1 1260/4885VDR 76/4885CYP2C9 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.