Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23382294 | 0.77 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL21958547 | 0.77 | GRM1 (0.38) | GRM1ALDH1A1 | |
| SCHEMBL29750581 | 0.75 | ALDH1A1 (0.37) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17680242 | 0.74 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL20674173 | 0.73 | HPGD (0.41) | MEN1KMT2AKDM4EALDH1A1APP | |
| SCHEMBL24597613 | 0.73 | ALDH1A1 (0.33) | MEN1KMT2AKDM4EALDH1A1APP | |
| SCHEMBL24597614 | 0.73 | TSHR (0.35) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23937882 | 0.73 | GRM1 (0.36) | GRM1SMN1; SMN2ALOX15 | |
| SCHEMBL22778947 | 0.70 | CACNA1H (0.40) | MEN1KMT2ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL3345735 | 0.69 | USP7 (0.40) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |