Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958679 | 0.87 | — | — | |
| SCHEMBL20952915 | 0.75 | — | — | |
| SCHEMBL21959597 | 0.74 | — | — | |
| SCHEMBL20674457 | 0.73 | GRM5 (0.38) | — | |
| SCHEMBL23937918 | 0.72 | BRD4 (0.40) | PARP1 | |
| SCHEMBL17505258 | 0.70 | ALDH1A1 (0.43) | PARP1 | |
| SCHEMBL23937897 | 0.67 | PARP1 (0.33) | PARP1PARP15PARP3 | |
| SCHEMBL21196044 | 0.64 | CYP2C19 (0.34) | — | |
| SCHEMBL21216436 | 0.63 | SOD3 (0.35) | — | |
| Bromide SCHEMBL21196019 | 0.62 | SOD3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |