Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MMP12 | P39900 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | MMP14 | P50281 | 2/20 | 0.53 |
| ▸ | MMP16 | P51512 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL7876282 | 0.98 | PTGS2 (0.58) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL8479916 | 0.94 | PTGS2 (0.58) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL8148942 | 0.89 | PTGS2 (0.51) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL28755926 | 0.89 | PTGS2 (0.51) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL1567195 | 0.86 | PTGS2 (0.44) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL11766705 | 0.85 | PPARG (0.49) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL27586367 | 0.85 | AKR1C3 (0.57) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL28472426 | 0.85 | AKR1C3 (0.58) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL10716503 | 0.85 | PTGS2 (0.43) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL2391809 | 0.85 | BCAT2 (0.48) | PTGS2MMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195634-B | Preparation method of 2-biphenyl propionic acid compound | 上海惠永药物研究有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-114195634-A | Preparation method of 2-biphenylyl propionic acid compound | 上海惠永药物研究有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-5196567-A | Analgesics, antiinflammatory, antipyretic, fewer side effects | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-03-23 | — | — | US | claimed |
| US-4699925-A | ANTIINFLAMMATORY AGENTS, ANALGESICS AND-OR ANTIPYRETICS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1987-10-13 | — | — | US | claimed |
| EP-0103265-B1 | BIPHENYLYLPROPIONIC ACID DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-12-03 | — | — | EP | claimed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | claimed |
| JP-60016923-A | — | — | None | — | — | JP | disclosed |
| JP-60001122-A | — | — | None | — | — | JP | disclosed |
| CN-114195634-B | Preparation method of 2-biphenyl propionic acid compound | 上海惠永药物研究有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114195634-B | Preparation method of 2-biphenyl propionic acid compound | 上海惠永药物研究有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117551097-A | Sophoridine tricyclic derivative and application thereof in preparation of medicines for resisting hepatic fibrosis or liver cancer | 中国人民解放军海军军医大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-110140245-B | Nonaqueous electrolyte secondary battery and material used therein | 三井化学株式会社 | 2022-10-25 | — | — | CN | disclosed |
| CN-114195634-A | Preparation method of 2-biphenylyl propionic acid compound | 上海惠永药物研究有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-4699925-A | ANTIINFLAMMATORY AGENTS, ANALGESICS AND-OR ANTIPYRETICS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1987-10-13 | — | — | US | disclosed |
| US-4699925-A | ANTIINFLAMMATORY AGENTS, ANALGESICS AND-OR ANTIPYRETICS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1987-10-13 | — | — | US | disclosed |
| JP-S6016923-A | FAT EMULSION OF BIPHENYLYLPROPIONIC ACID DERIVATIVE | GREEN CROSS CORP:THE | 1985-01-28 | — | — | JP | disclosed |
| JP-S601122-A | FAT EMULSION OF BIPHENYLYLPROPIONIC ACID DERIVATIVE | GREEN CROSS CORP:THE | 1985-01-07 | — | — | JP | disclosed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | disclosed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4014993-A | Inhibition of platelet aggregation with substituted phenylhydratropic acid compounds | THE UPJOHN COMPANY (US) | 1977-03-29 | — | — | US | disclosed |