Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MMP12 | P39900 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 2/20 | 0.55 |
| ▸ | MMP16 | P51512 | 2/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | FABP2 | P12104 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393839 | 0.98 | PTGS2 (0.56) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL8479916 | 0.92 | PTGS2 (0.58) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL28755926 | 0.87 | PTGS2 (0.51) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL8148942 | 0.87 | PTGS2 (0.51) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL1567195 | 0.85 | PTGS2 (0.44) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL11766705 | 0.84 | PPARG (0.49) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL28472426 | 0.83 | AKR1C3 (0.58) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL27586367 | 0.83 | AKR1C3 (0.57) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL2391809 | 0.83 | BCAT2 (0.48) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL10716503 | 0.83 | PTGS2 (0.43) | PTGS2MMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172262-B1 | CONTAINING AMIDE; DETERGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2001-01-09 | — | — | US | disclosed |