SCHEMBL2393906

SCHEMBL2393906

Brc1ccc(-c2sc(-c3ccc(Br)cc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
MAPK1 P28482 2/20 0.58
CYP3A4 P08684 3/20 0.45
MAPT P10636 3/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
NR1H4 Q96RI1 1/20 0.40
TP53 P04637 1/20 0.40
MDM2 Q00987 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24817276 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1CYP3A4MAPTKDM4E
SCHEMBL1224397 0.86 MAPT (0.56) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL5250848 0.81 ALDH1A1 (0.78) ALDH1A1MAPK1MAPTNPC1NFKB1
SCHEMBL10019513 0.81 ALDH1A1 (0.78) ALDH1A1MAPK1MAPTNPC1NFKB1
SCHEMBL5804045 0.81 ALDH1A1 (0.78) ALDH1A1MAPK1MAPTNPC1NFKB1
SCHEMBL23232540 0.80 MAPT (0.41) ALDH1A1MAPK1CYP3A4MAPTKDM4E
SCHEMBL9364153 0.80 CYP3A4 (0.61) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL8582553 0.80 CYP3A4 (0.61) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL9364149 0.80 CYP3A4 (0.61) ALDH1A1CYP3A4MAPTKDM4ECYP1A2
SCHEMBL9325209 0.80 CYP3A4 (0.61) ALDH1A1CYP3A4MAPTKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347878-B1 Method for manufacturing polyamide resin TOSOH CORP (JP) 1994-09-07 EP claimed
EP-0530705-A1 Method for producing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530703-A2 Method for the preparation of polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
US-4948864-A Catalytic method for manufacturing aromatic polyester resin from aromatic diol, aromatic dibromide and carbon monoxide TOSOH CORPORATION (JP) 1990-08-14 US claimed
US-4937313-A Method for manufacturing polyamide resin from unsaturated bis-amide and arylene dihalide TOSOH CORPORATION (JP) 1990-06-26 US claimed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP claimed
EP-0347878-A2 Method for manufacturing polyamide resin Tosoh Corporation (JP) 1989-12-27 EP claimed
EP-1935919-B1 POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER YAMAMOTO CHEMICALS INC (JP) 2012-09-05 EP disclosed
US-8012608-B2 Polymer containing sulfo group and organic electroluminescent element containing the polymer Yamamoto Chemcials, Inc. (JP) 2011-09-06 US disclosed
US-20090230851-A1 Polymer Containing Sulfo Group and Organic Electroluminescent Element Containing the Polymer MITSUI CHEMICALS, INC. (JP) 2009-09-17 US disclosed
EP-1935919-A1 POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER Mitsui Chemicals, Inc. (JP) 2008-06-25 EP disclosed
EP-0347878-B1 Method for manufacturing polyamide resin TOSOH CORP (JP) 1994-09-07 EP disclosed
EP-0530705-A1 Method for producing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed
EP-0530703-A2 Method for the preparation of polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed
US-4948864-A Catalytic method for manufacturing aromatic polyester resin from aromatic diol, aromatic dibromide and carbon monoxide TOSOH CORPORATION (JP) 1990-08-14 US disclosed
US-4937313-A Method for manufacturing polyamide resin from unsaturated bis-amide and arylene dihalide TOSOH CORPORATION (JP) 1990-06-26 US disclosed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP disclosed
EP-0347878-A2 Method for manufacturing polyamide resin Tosoh Corporation (JP) 1989-12-27 EP disclosed