Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24317058 | 0.73 | HTR1D (0.42) | HTR1DHTR1BMCHR1 | |
| SCHEMBL24317011 | 0.69 | DRD2 (0.46) | HTR1DHTR1BMCHR1 | |
| SCHEMBL20006795 | 0.65 | HTR1D (0.38) | HTR1DHTR1BSGPL1MCHR1 | |
| SCHEMBL20006880 | 0.64 | HTR1D (0.45) | HTR1DHTR1BOPRL1MCHR1 | |
| SCHEMBL20007096 | 0.64 | DRD2 (0.46) | HTR1DHTR1B | |
| SCHEMBL26543317 | 0.62 | SGPL1 (0.38) | HTR1DHTR1BSGPL1MCHR1 | |
| SCHEMBL19186568 | 0.61 | MCHR1 (0.41) | HTR1DHTR1BTP53MCHR1 | |
| SCHEMBL18137140 | 0.60 | HTR1D (0.48) | HTR1DHTR1BOPRL1MCHR1 | |
| SCHEMBL6160107 | 0.60 | HTR1D (0.55) | HTR1DHTR1BSGPL1MCHR1 | |
| SCHEMBL6160101 | 0.60 | HTR1D (0.55) | HTR1DHTR1BSGPL1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |