Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006948 | 0.83 | DRD2 (0.54) | HTR1DHTR1BMCHR1SLC6A4ADRA2A | |
| SCHEMBL24317059 | 0.81 | HTR1D (0.49) | HTR1DHTR1BMCHR1SLC6A4ADRA2A | |
| SCHEMBL20006770 | 0.77 | HTR1D (0.52) | HTR1DHTR1BMCHR1SLC6A4ADRA2A | |
| SCHEMBL24316813 | 0.77 | HTR1D (0.39) | HTR1DHTR1BSLC6A4ADRA2AADRA2B | |
| SCHEMBL23940661 | 0.76 | HTR1D (0.48) | HTR1DHTR1BMCHR1SLC6A4ADRA2A | |
| SCHEMBL23940696 | 0.76 | HTR1D (0.48) | HTR1DHTR1BMCHR1SLC6A4ADRA2A | |
| SCHEMBL20006795 | 0.73 | HTR1D (0.38) | HTR1DHTR1BMCHR1SLC6A4ADRA2A | |
| SCHEMBL18900425 | 0.73 | ALDH1A1 (0.35) | HTR1DHTR1BMCHR1OPRK1DGAT1 | |
| SCHEMBL20007096 | 0.72 | DRD2 (0.46) | HTR1DHTR1BSLC6A4ADRA2AADRA2B | |
| SCHEMBL24317058 | 0.71 | HTR1D (0.42) | HTR1DHTR1BMCHR1SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2018-03-28 | — | — | EP | disclosed |