Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678560 | 0.87 | EGFR (0.57) | BACE1TBXAS1EGFRIAPPCAPN1 | |
| SCHEMBL2233170 | 0.85 | ALOX5 (0.50) | BACE1IAPPESR1CAPN1ESR2 | |
| SCHEMBL16001868 | 0.83 | MEN1 (0.48) | BACE1ESR1MEN1ALDH1A1MAPT | |
| SCHEMBL2388960 | 0.83 | BACE1 (0.46) | BACE1TBXAS1EGFRIAPPESR1 | |
| SCHEMBL2392661 | 0.83 | KMT2A (0.47) | TBXAS1EGFRIAPPESR1CAPN1 | |
| SCHEMBL2389163 | 0.81 | CYP2C9 (0.46) | TBXAS1EGFRESR1MEN1ALDH1A1 | |
| SCHEMBL5173409 | 0.80 | TBXAS1 (0.58) | TBXAS1EGFRESR1MEN1ALDH1A1 | |
| SCHEMBL1405662 | 0.80 | MAPT (0.60) | BACE1EGFRMEN1ALDH1A1MAPT | |
| SCHEMBL10350136 | 0.80 | MAPT (0.60) | BACE1EGFRMEN1ALDH1A1MAPT | |
| SCHEMBL3637129 | 0.80 | MAPT (0.60) | BACE1EGFRMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |