Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515290 | 0.87 | TBXAS1 (0.48) | KMT2AMEN1TBXAS1ESR1 | |
| SCHEMBL9515296 | 0.87 | TBXAS1 (0.48) | KMT2AMEN1TBXAS1ESR1 | |
| SCHEMBL6678560 | 0.85 | EGFR (0.57) | KMT2AMEN1ALDH1A1TBXAS1EGFR | |
| SCHEMBL1907796 | 0.83 | DPEP1 (0.49) | TBXAS1ESR1 | |
| SCHEMBL2394174 | 0.83 | DPEP1 (0.49) | TBXAS1ESR1 | |
| SCHEMBL2394182 | 0.83 | BACE1 (0.47) | KMT2AMEN1ALDH1A1TBXAS1EGFR | |
| SCHEMBL2388960 | 0.81 | BACE1 (0.46) | KMT2AMEN1TBXAS1EGFRIAPP | |
| SCHEMBL2389154 | 0.81 | PSEN1 (0.51) | KMT2AMEN1ALDH1A1PKM | |
| SCHEMBL5173409 | 0.79 | TBXAS1 (0.58) | KMT2AMEN1ALDH1A1TBXAS1EGFR | |
| SCHEMBL1405662 | 0.79 | MAPT (0.60) | KMT2AMEN1ALDH1A1PKMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |