Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944980 | 0.74 | JAK3 (0.41) | CHRM2CHRNA7 | |
| SCHEMBL19960986 | 0.69 | PER2 (0.36) | CHRM2CHRNA7 | |
| SCHEMBL19960978 | 0.67 | HTR2A (0.36) | CHRM2CHRNA7 | |
| SCHEMBL23944977 | 0.66 | PER2 (0.36) | — | |
| SCHEMBL19960987 | 0.64 | HTR2A (0.42) | — | |
| SCHEMBL19960982 | 0.62 | CHRM2 (0.32) | CHRM2CHRNA7 | |
| SCHEMBL19960989 | 0.62 | GPR3 (0.31) | — | |
| SCHEMBL19960984 | 0.62 | CHRM2 (0.30) | CHRM2CHRNA7 | |
| SCHEMBL14372628 | 0.61 | JAK3 (0.69) | — | |
| SCHEMBL14372629 | 0.61 | JAK3 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323976-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ARIAD PHARMACEUTICALS, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323976-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ERBB2, EGFR, ERBB3 | CHRM2 4351/4885CHRNA7 4447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.