Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 14/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913684 | 1.00 | MTNR1B (0.53) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL23944996 | 1.00 | MTNR1B (0.53) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL12056681 | 0.78 | MTNR1B (0.62) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL12056670 | 0.78 | MTNR1B (0.62) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL3338295 | 0.78 | MTNR1B (0.62) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL3338269 | 0.78 | MTNR1B (0.62) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL12056687 | 0.78 | MTNR1A (0.51) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL28361577 | 0.76 | MTNR1B (0.67) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL28030985 | 0.76 | MTNR1B (0.49) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL13705943 | 0.74 | MTNR1B (0.61) | MTNR1BMTNR1AABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210920-A1 | METHOD FOR PRODUCING RAMELTEON, AND INTERMEDIATE COMPOUND USED FOR SAME | 제이투에이치바이오텍 주식회사 | 2021-10-21 | — | — | WO | disclosed |