Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 12/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913684 | 0.76 | MTNR1B (0.53) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL23944996 | 0.76 | MTNR1B (0.53) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL23944989 | 0.76 | MTNR1B (0.53) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL12056682 | 0.73 | MTNR1B (0.58) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL7419740 | 0.73 | PIN1 (0.51) | MTNR1BMTNR1AALDH1A1 | |
| SCHEMBL23934507 | 0.72 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2NPC1TSHR | |
| SCHEMBL12056691 | 0.69 | MTNR1B (0.68) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL12056690 | 0.69 | MTNR1B (0.68) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL12056689 | 0.69 | MTNR1B (0.68) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL803818 | 0.69 | MTNR1A (0.62) | MTNR1BMTNR1AABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910109-A | A preparation method of 2-(2, 6,7, 8-tetrahydro-1H-indeno [5,4-b] furan-8-yl) acrylic acid ethyl ester as key intermediate for synthesizing ramelteon amine | SHANGHAI KEEPONTECH CO LTD | 2015-09-16 | — | — | CN | disclosed |
| CN-104910109-A | A preparation method of 2-(2, 6,7, 8-tetrahydro-1H-indeno [5,4-b] furan-8-yl) acrylic acid ethyl ester as key intermediate for synthesizing ramelteon amine | SHANGHAI KEEPONTECH CO LTD | 2015-09-16 | — | — | CN | disclosed |