SCHEMBL23945235

SCHEMBL23945235

Clc1ccc(-c2nc3cc4ccccc4cc3n2-c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.51
AOC3 Q16853 3/20 0.48
KCNH2 Q12809 1/20 0.48
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 1/20 0.46
GLA P06280 1/20 0.45
CYP1A2 P05177 1/20 0.44
GAA P10253 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
SIRT2 Q8IXJ6 1/20 0.44
SIRT1 Q96EB6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24477061 0.89 ESR1 (0.54) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL8027341 0.87 RAB9A (0.60) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL8931017 0.85 MAPK10 (0.44) AOC3NPC1RAB9AKDM4ELMNA
SCHEMBL3741438 0.84 PTGS2 (0.53) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL8022202 0.83 PTGS2 (0.69) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL20776032 0.82 NPC1 (0.54) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL23024881 0.82 RAB9A (0.66) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL2323575 0.82 ESR1 (0.58) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL2330775 0.81 GLA (0.57) PTGS2AOC3KCNH2NPC1RAB9A
SCHEMBL29023856 0.81 KDM4E (0.47) PTGS2AOC3KCNH2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328149-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-10-21 US disclosed