Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 7/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477061 | 0.89 | ESR1 (0.54) | ESR1ESR2SIRT2SIRT1ALDH1A1 | |
| SCHEMBL8011262 | 0.88 | ESR1 (0.57) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL21674159 | 0.87 | SIRT2 (0.46) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL14506132 | 0.86 | ESR1 (0.56) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL14506131 | 0.86 | ESR1 (0.56) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL23945057 | 0.86 | SIRT2 (0.45) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL23945056 | 0.86 | SIRT2 (0.45) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL23945062 | 0.86 | SIRT2 (0.45) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL12278691 | 0.85 | PTGER4 (0.40) | MAPK10ESR1ESR2SIRT2SIRT1 | |
| SCHEMBL23945235 | 0.85 | PTGS2 (0.51) | ESR1ESR2SIRT2SIRT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187727-B2 | Imidazole derivatives, preparation method thereof and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-05-29 | — | — | US | disclosed |
| US-8187727-B2 | Imidazole derivatives, preparation method thereof and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-05-29 | — | — | US | disclosed |
| WO-2007011170-A9 | NEW IMIDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM. LTD. (KR) | 2011-06-16 | — | — | WO | disclosed |
| EP-1907366-B1 | NEW IMIDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEMICAL LTD (KR) | 2010-04-28 | — | — | EP | disclosed |
| US-20070018155-A1 | New imidazole derivatives, preparation method thereof and organic electronic device using the same | LG CHEM. LTD. (KR) | 2007-01-25 | — | — | US | disclosed |
| US-20070018155-A1 | New imidazole derivatives, preparation method thereof and organic electronic device using the same | LG CHEM. LTD. (KR) | 2007-01-25 | — | — | US | disclosed |
| WO-2007011170-A1 | NEW IMIDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM. LTD. (KR) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070018155-A1 | New imidazole derivatives, preparation method thereof and organic electronic device using the same | ICMT, TIMM9, TIMM44 | MAPK10 2878/4885ESR1 302/4885ESR2 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.