Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628707 | 1.00 | TSHR (0.54) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL2434823 | 1.00 | TSHR (0.54) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28182671 | 0.87 | LMNA (0.61) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL72654 | 0.83 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL17714426 | 0.82 | TSHR (0.57) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL3234177 | 0.82 | TSHR (0.57) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL2971855 | 0.81 | LMNA (0.54) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28041527 | 0.81 | TSHR (0.47) | TSHRLMNAALDH1A1TDP1HSD17B10 | |
| Benzoic Acid Vinyl Ester SCHEMBL28299446 | 0.80 | TSHR (0.50) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL27757178 | 0.80 | TSHR (0.50) | TSHRLMNAF2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211423-A1 | METHODS FOR DEPOLYMERIZING POLYESTERS | NORTHWESTERN UNIVERSITY (US) | 2021-10-21 | — | — | WO | disclosed |