SCHEMBL628707

SCHEMBL628707

CC=COC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.54
LMNA P02545 2/20 0.52
F2 P00734 1/20 0.52
ALDH1A1 P00352 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
HSD17B10 Q99714 1/20 0.46
TP53 P04637 1/20 0.44
PLA2G7 Q13093 1/20 0.43
KMT2A Q03164 4/20 0.42
MAPT P10636 3/20 0.42
SLC6A3 Q01959 2/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
POLB P06746 1/20 0.42
SLC6A2 P23975 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2434823 1.00 TSHR (0.54) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL23945318 1.00 TSHR (0.54) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL28182671 0.87 LMNA (0.61) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL72654 0.83 TSHR (0.58) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL17714426 0.82 TSHR (0.57) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL3234177 0.82 TSHR (0.57) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL2971855 0.81 LMNA (0.54) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL28041527 0.81 TSHR (0.47) TSHRLMNAALDH1A1TDP1HSD17B10
Benzoic Acid Vinyl Ester SCHEMBL28299446 0.80 TSHR (0.50) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL27757178 0.80 TSHR (0.50) TSHRLMNAF2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9279085-B2 Method for the production of monofunctionalized dialkylphosphinic acids, esters and salts, and use thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2016-03-08 US claimed
US-8735476-B2 Method for producing mono-carboxy-functionalized dialkylphosphinic acids, esters and salts using a vinyl ester of a carboxylic acid and the use thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-05-27 US claimed
EP-2373667-B1 METHOD FOR PRODUCING MONO-CARBOXY-FUNCTIONALIZED DIALKYLPHOSPHINIC ACIDS, ESTERS AND SALTS USING A VINYL ESTER OF A CARBOXYLIC ACID AND THE USE THEREOF CLARIANT FINANCE BVI LTD (VG) 2013-12-11 EP claimed
US-20110237721-A1 Method for Producing Mono-Carboxy-Functionalized Dialkylphosphinic Acids, Esters and Salts Using a Vinyl Ester of a Carboxylic Acid and the Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2011-09-29 US claimed
US-12508218-B2 Coating compositions COTY INC. (US) 2025-12-30 US disclosed
US-20250127707-A1 FRAGRANCE FORMULATION COTY INC. 2025-04-24 US disclosed
CN-116783160-A Libraries of compounds 中外制药株式会社 2023-09-19 CN disclosed
US-20230285261-A1 FRAGRANCE COMPOSITION COMPRISING A FRAGRANCE COMPONET AND A NON-ODOROUS FRAGRANCE MODULATOR JPMORGAN CHASE BANK, N.A. 2023-09-14 US disclosed
CN-109851598-B Preparation method of trifluoromethyl substituted trans enol ester 江西师范大学 2022-11-29 CN disclosed
US-20220304914-A1 COATING COMPOSITIONS JPMORGAN CHASE BANK, N.A. 2022-09-29 US disclosed
CN-111684035-B Acrylic emulsion pressure sensitive adhesive composition 株式会社LG化学 2022-04-12 CN disclosed
CN-106062068-B Thermoplastic composition based on polypropylene and polyamide-grafted polyolefin 阿肯马法国公司 2020-11-27 CN disclosed
US-20020004594-A1 Phosphoramidates and methods therefor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-01-10 US disclosed
WO-2001074827-A1 PHOSPHORAMIDATE PRODRUGS PURDUE RESEARCH FOUNDATION (US) 2001-10-11 WO disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-0513331-A1 AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-11-19 EP disclosed
WO-1992009554-A1 AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-06-11 WO disclosed
US-4192684-A Photosensitive compositions containing hydrogenated 1,2-polybutadiene ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-03-11 US disclosed
US-4006024-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-02-01 US disclosed
US-3960572-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220304914-A1 COATING COMPOSITIONS OR10J3, OR51E2, TAS2R20 TSHR 4724/4885LMNA 3674/4885F2 1987/4885
US-20020004594-A1 Phosphoramidates and methods therefor WEE1, HASPIN, WEE2 TSHR 3813/4885LMNA 3858/4885F2 4652/4885
US-20110237721-A1 Method for Producing Mono-Carboxy-Functionalized Dialkylphosphinic Acids, Esters and Salts Using a Vinyl Ester of a Carboxylic Acid and the Use Thereof SCO2, HAO2, DAO TSHR 1600/4885LMNA 2720/4885F2 502/4885
US-20250127707-A1 FRAGRANCE FORMULATION PUF60, POLM, ADH5 TSHR 4700/4885LMNA 3368/4885F2 400/4885
US-20230285261-A1 FRAGRANCE COMPOSITION COMPRISING A FRAGRANCE COMPONET AND A NON-ODOROUS FRAGRANCE MODULATOR OR51E2, TRPA1, FAM120A TSHR 4726/4885LMNA 3776/4885F2 920/4885
US-12508218-B2 Coating compositions TAS2R40, TAS2R20, TAS2R10 TSHR 3449/4885LMNA 3689/4885F2 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.