Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686849 | 0.83 | CYP1A2 (0.64) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| Formaldehyde SCHEMBL28179692 | 0.81 | CYP1A2 (0.57) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| SCHEMBL11859921 | 0.76 | ACHE (0.48) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| SCHEMBL1046000 | 0.76 | ALDH1A1 (0.48) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| SCHEMBL23297418 | 0.76 | CYP1A2 (0.42) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| SCHEMBL4846739 | 0.76 | TAAR1 (0.44) | CYP1A2CYP1A1CYP1B1ALDH1A1CA9 | |
| SCHEMBL18040901 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| SCHEMBL27581475 | 0.76 | ALOX15 (0.47) | ACHECA9CYP3A4MAPTCA1 | |
| SCHEMBL34336 | 0.75 | ALDH1A1 (0.53) | CYP1A2CYP1A1CYP1B1ALDH1A1CA9 | |
| SCHEMBL684136 | 0.74 | ACHE (0.52) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078482-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-05-11 | — | — | WO | claimed |
| EP-0117961-B1 | HETEROCYCLIC DERIVATIVES SUBSTITUTED BY AN AMINO RADICAL, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Albert ROLLAND S.A. Société dite (FR) | 1991-04-03 | — | — | EP | claimed |
| US-4647557-A | Novel heterocyclic derivatives bearing an amino radical, processes for their production and the pharmaceutical compositions containing them | MOINET GERARD (FR) | 1987-03-03 | — | — | US | claimed |
| WO-2023078482-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-05-11 | — | — | WO | disclosed |
| EP-2043630-B1 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES FOR COSMETIC USE | INST OF EX BOTANY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2016-09-07 | — | — | EP | disclosed |
| US-20130072505-A1 | 6,9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE (CZ) | 2013-03-21 | — | — | US | disclosed |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE | 2011-09-15 | — | — | US | disclosed |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | SZUCOVA LUCIE | 2010-09-16 | — | — | US | disclosed |
| EP-2043630-A2 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE FOR TREATING SKIN | Institute of Experimental Botany, Academy of Sciences of the Czech Republic (CZ) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008770-A2 | 6, 9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE FOR TREATING SKIN | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-17 | — | — | WO | disclosed |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-10 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4826861-A | MEDICAL BACTERICIDES OR FUNGICIDES | ALBERT ROLAND, S.A. (FR) | 1989-05-02 | — | — | US | disclosed |
| EP-0245417-A1 | NEW PROCESS FOR OBTAINING ALPHA-AMINO NITRILES AND THEIR APPLICATIONS TO ORGANIC SYNTHESIS. | ROLLAND SA A (FR) | 1987-11-19 | — | — | EP | disclosed |
| WO-1987002980-A1 | NEW PROCESS FOR OBTAINING alpha-AMINO NITRILES AND THEIR APPLICATIONS TO ORGANIC SYNTHESIS | ALBERT ROLLAND S.A. (FR) | 1987-05-21 | — | — | WO | disclosed |
| US-4647557-A | Novel heterocyclic derivatives bearing an amino radical, processes for their production and the pharmaceutical compositions containing them | MOINET GERARD (FR) | 1987-03-03 | — | — | US | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4497815-A | 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the carcinostatic agents containing same as active ingredients | Ozaki, Shoichiro (JP) | 1985-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | UNG, P2RY6, MPG | CYP1A2 2278/4885CYP1A1 2410/4885CYP1B1 1153/4885 |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | CYP1A2 2278/4885CYP1A1 2410/4885CYP1B1 1153/4885 |
| US-20130072505-A1 | 6,9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | CYP1A2 2278/4885CYP1A1 2410/4885CYP1B1 1153/4885 |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | UNG, P2RY6, MPG | CYP1A2 2278/4885CYP1A1 2410/4885CYP1B1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.