Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23946344 | 0.91 | TOP1 (0.54) | TOP1NPC1RAB9ASMN1; SMN2PDGFRB | |
| SCHEMBL9885994 | 0.86 | MET (0.54) | TOP1NPC1RAB9ASMN1; SMN2PDGFRB | |
| SCHEMBL23946299 | 0.85 | TOP1 (0.49) | TOP1NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13019020 | 0.81 | NPC1 (0.53) | TOP1NPC1RAB9ASMN1; SMN2PDGFRB | |
| SCHEMBL7069625 | 0.81 | NPC1 (0.60) | TOP1NPC1RAB9ASMN1; SMN2PDGFRB | |
| SCHEMBL11987282 | 0.80 | ATR (0.47) | TOP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13078957 | 0.79 | RAB9A (0.44) | TOP1NPC1RAB9ASMN1; SMN2PDGFRB | |
| SCHEMBL29371290 | 0.77 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2PDGFRBKDR | |
| SCHEMBL87505 | 0.77 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2PDGFRBKDR | |
| SCHEMBL20619889 | 0.75 | TOP1 (0.40) | TOP1NPC1RAB9ASMN1; SMN2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | IDO1, IDO2, AZI2 | TOP1 2508/4885NPC1 4806/4885RAB9A 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.