SCHEMBL23946299

SCHEMBL23946299

c1ccc(-c2cccc3nc(-c4cccc5ccccc45)cnc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 6/20 0.49
ATR Q13535 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
NOS1 P29475 1/20 0.44
TNF P01375 1/20 0.44
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
MAPK1 P28482 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23946344 0.87 TOP1 (0.54) TOP1ATRTNFSMN1; SMN2MAPK1
SCHEMBL23946379 0.85 TOP1 (0.60) TOP1MAPTSMN1; SMN2ALDH1A1MAPK1
SCHEMBL2243516 0.80 KDM4E (0.52) ATRMEN1KMT2ANOS1KDM4E
SCHEMBL18101991 0.78 ATR (0.43) ATRMEN1KMT2ANOS1KDM4E
SCHEMBL19009479 0.76 NOS1 (0.52) ATRMEN1KMT2ANOS1KDM4E
SCHEMBL12722972 0.76 NOS1 (0.52) ATRMEN1KMT2ANOS1KDM4E
SCHEMBL24596449 0.74 TLR9 (0.53) TOP1KDM4EMAPTSMN1; SMN2ALDH1A1
SCHEMBL11987282 0.73 ATR (0.47) TOP1ATRSMN1; SMN2TP53HPGD
2-Phenylquinoline SCHEMBL18107977 0.73 RAB9A (0.54) MEN1KMT2ATNFKDM4EMAPT
SCHEMBL9885994 0.72 MET (0.54) TOP1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 TOP1 2508/4885ATR 3057/4885MEN1 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.