⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762908 | 1.00 | — | — | |
| SCHEMBL19362272 | 1.00 | — | — | |
| SCHEMBL8494551 | 0.82 | — | — | |
| SCHEMBL20850665 | 0.82 | — | — | |
| SCHEMBL2511403 | 0.78 | TDP1 (0.44) | — | |
| SCHEMBL19788207 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL22088567 | 0.75 | — | — | |
| SCHEMBL7162514 | 0.73 | HTR2A (0.40) | — | |
| SCHEMBL141055 | 0.73 | — | — | |
| SCHEMBL27306247 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322575-A1 | LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY | NUTCRACKER THERAPEUTICS, INC. (US) | 2021-10-21 | — | — | US | disclosed |