⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20850665 | 1.00 | — | — | |
| SCHEMBL7762908 | 0.82 | — | — | |
| SCHEMBL19362272 | 0.82 | — | — | |
| SCHEMBL23948105 | 0.82 | — | — | |
| SCHEMBL2514474 | 0.80 | ALDH1A1 (0.47) | — | |
| SCHEMBL105238 | 0.77 | — | — | |
| SCHEMBL25563971 | 0.75 | PIK3CD (0.45) | — | |
| SCHEMBL3009232 | 0.75 | — | — | |
| SCHEMBL10945633 | 0.75 | LMNA (0.37) | — | |
| Hydrochloric Acid SCHEMBL27462561 | 0.74 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |
| US-11000512-B2 | Use of DDX3 inhibitors as antiproliferative agents | AZIENDA OSPEDALIERA UNIVERSITARIA SENESE (IT) | 2021-05-11 | — | — | US | disclosed |
| US-10941121-B2 | Human helicase DDX3 inhibitors as therapeutic agents | AZIENDA OSPEDALIERA UNIVERSITARIA SENESE (IT) | 2021-03-09 | — | — | US | disclosed |
| US-20190099403-A1 | USE OF DDX3 INHIBITORS AS ANTIPROLIFERATIVE AGENTS | AZIENDA OSPEDALIERA UNIVERSITARIA SENRESE (IT) | 2019-04-04 | — | — | US | disclosed |
| EP-0676237-B1 | Modified ion exchange resins and use thereof | MITSUBISHI CHEM CORP (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5589517-A | N,N-DI-SUBSTITITUTED MERCAPTOALKYLAMINE SULFONIC ACID ION EXCHANGE RESIN AS CATALYST FOR CONDENSATION REACTION OF A PHENOL AND A KETONE TO PRODUCE A BISPHENOL | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0676237-A1 | Modified ion exchange resins and use thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-11 | — | — | EP | disclosed |