Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497308 | 0.89 | TDP1 (0.36) | TDP1HTR2AHRH1ALDH1A1TSHR | |
| SCHEMBL21533051 | 0.89 | TDP1 (0.36) | TDP1HTR2AHRH1ALDH1A1TSHR | |
| SCHEMBL8494447 | 0.85 | — | — | |
| SCHEMBL8496735 | 0.84 | DNM1 (0.44) | TDP1HTR2AHRH1ALDH1A1TSHR | |
| SCHEMBL15086048 | 0.83 | DNM1 (0.48) | ALDH1A1TSHRDNM1 | |
| SCHEMBL2514474 | 0.81 | ALDH1A1 (0.47) | TDP1HTR2AHRH1ALDH1A1TSHR | |
| SCHEMBL18519801 | 0.81 | DNM1 (0.52) | ALDH1A1TSHRDNM1 | |
| SCHEMBL23948105 | 0.78 | — | — | |
| SCHEMBL7762908 | 0.78 | — | — | |
| SCHEMBL19362272 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356171-B1 | SILOXANE COPOLYMERS AND METHODS FOR PRODUCTION THEREOF | WACKER CHEMIE AG (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-20110245144-A1 | SILOXANE COPOLYMERS AND METHODS FOR PRODUCTION THEREOF | WACKER CHEMIE AG | 2011-10-06 | — | — | US | disclosed |
| US-7427648-B2 | Hydrophilic siloxane copolymers and process for the preparation thereof | WACKER CHEMIE AG (DE) | 2008-09-23 | — | — | US | disclosed |
| EP-1607427-B1 | Hydrophilic siloxane copolymers and process for their preparation | WACKER CHEMIE AG (DE) | 2006-08-23 | — | — | EP | disclosed |
| EP-1607427-A1 | Hydrophilic siloxane copolymers and process for their preparation | Wacker-Chemie GmbH (DE) | 2005-12-21 | — | — | EP | disclosed |
| US-20050272862-A1 | Hydrophilic siloxane copolymers and process for the preparation thereof | WACKER-CHEMIE GMBH (DE) | 2005-12-08 | — | — | US | disclosed |