SCHEMBL2394831

SCHEMBL2394831

CCC1(CO)COC(=O)N1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.32
NPSR1 Q6W5P4 1/20 0.31
POLB P06746 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446549 0.88 NPSR1 (0.34) MGLLNPSR1POLBKDM4E
SCHEMBL3420125 0.88 KDM4E (0.32) MGLLKDM4E
SCHEMBL7153643 0.77
SCHEMBL4455670 0.76 S1PR1 (0.33) MGLL
SCHEMBL12427227 0.75 MGLL (0.32) MGLL
SCHEMBL4459894 0.73 S1PR1 (0.37) KDM4E
SCHEMBL9735802 0.73 KDM4E (0.31) POLBKDM4EGAA
SCHEMBL7070377 0.73 KDM4E (0.31) POLBKDM4EGAA
SCHEMBL1439232 0.72
SCHEMBL2391518 0.72 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064645-A1 Biocidal polyester and methods AUBURN UNIVERSITY 2003-04-03 US claimed
WO-2002006579-A2 BIOCIDAL POLYAMIDES AND METHODS AUBURN UNIVERSITY (US) 2002-01-24 WO claimed
US-8017665-B2 Ophthalmic devices containing heterocyclic compounds and methods for their production JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-09-13 US disclosed
US-8017665-B2 Ophthalmic devices containing heterocyclic compounds and methods for their production JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-09-13 US disclosed
US-8017665-B2 Ophthalmic devices containing heterocyclic compounds and methods for their production JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-09-13 US disclosed
US-20100238399-A1 OPHTHALMIC DEVICES CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION JOHNSON & JOHNSON VISION CARE, INC. 2010-09-23 US disclosed
US-20100238399-A1 OPHTHALMIC DEVICES CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION JOHNSON & JOHNSON VISION CARE, INC. 2010-09-23 US disclosed
US-20100238399-A1 OPHTHALMIC DEVICES CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION JOHNSON & JOHNSON VISION CARE, INC. 2010-09-23 US disclosed
US-7767730-B2 Ophthalmic devices containing heterocyclic compounds and methods for their production JOHNSON & JOHNSON VISION CARE, INC. (US) 2010-08-03 US disclosed
US-7767730-B2 Ophthalmic devices containing heterocyclic compounds and methods for their production JOHNSON & JOHNSON VISION CARE, INC. (US) 2010-08-03 US disclosed
US-7767730-B2 Ophthalmic devices containing heterocyclic compounds and methods for their production JOHNSON & JOHNSON VISION CARE, INC. (US) 2010-08-03 US disclosed
WO-2002006579-A2 BIOCIDAL POLYAMIDES AND METHODS AUBURN UNIVERSITY (US) 2002-01-24 WO disclosed
US-6162452-A Surface active N-halamine compounds AUBURN UNIVERSITY (US) 2000-12-19 US disclosed
WO-1999029678-A1 MONOMERIC AND POLYMERIC SURFACE ACTIVE BIOCIDAL N-HALO-OXAZOLIDINONES AUBURN UNIVERSITY (US) 1999-06-17 WO disclosed
US-5902818-A N-HALOGENATED, OXAZOLIDINONE MONOMERS HAVING AN ACRYLIC ESTER GROUP AT THE 4-POSITION RELEASE SMALL AMOUNTS FREE HALOGENS; DISINFECTANTS SUCH AS MEDICAL AND DENTAL COATINGS, FABRICS; COST EFFICIENCY, PERFORMANCE AUBURN UNIVERSITY (US) 1999-05-11 US disclosed
US-5817652-A ATHEROSCLEROSIS GLAXO WELLCOME INC. (US) 1998-10-06 US disclosed
EP-0683773-B1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES WELLCOME FOUND (GB) 1997-09-17 EP disclosed
US-5422042-A Improved toughness and flexibility HUNTSMAN CORPORATION (US) 1995-06-06 US disclosed
US-5422042-A Improved toughness and flexibility HUNTSMAN CORPORATION (US) 1995-06-06 US disclosed
WO-1994018184-A1 HYPOLIPIDAEMIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1994-08-18 WO disclosed