Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050797 | 0.85 | POLB (0.30) | KDM4EPOLBGAA | |
| SCHEMBL7070377 | 0.83 | KDM4E (0.31) | KDM4EPOLBGAAALDH1A1MAPT | |
| SCHEMBL5323355 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL2394831 | 0.73 | MGLL (0.32) | KDM4EPOLBGAA | |
| SCHEMBL7068994 | 0.71 | — | — | |
| SCHEMBL7067960 | 0.69 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL7048987 | 0.69 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL28740510 | 0.66 | EPHX1 (0.40) | KDM4EPOLBGAAALDH1A1MAPT | |
| SCHEMBL10836554 | 0.66 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9863702 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089614-A | Polysubstituted 2-morpholones | THE B. F. GOODRICH COMPANY (US) | 1992-02-18 | — | — | US | disclosed |
| US-4914232-A | FOR POLYMERS | THE B. F. GOODRICH COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4528370-A | Polysubstituted 2-morpholones | NOVEON IP HOLDINGS CORP., FORMERLY KNOWN AS PMD HOLDINGS CORP. | 1985-07-09 | — | — | US | disclosed |