SCHEMBL3420125

SCHEMBL3420125

O=C1NC(CO)(CO)CO1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
MGLL Q99685 7/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2394831 0.88 MGLL (0.32) KDM4EMGLL
SCHEMBL7153643 0.83
SCHEMBL4446549 0.77 NPSR1 (0.34) KDM4EMGLL
SCHEMBL4455670 0.74 S1PR1 (0.33) MGLL
SCHEMBL1439232 0.74
SCHEMBL19814031 0.72
SCHEMBL4459894 0.71 S1PR1 (0.37) KDM4E
SCHEMBL8976625 0.68 TSHR (0.34) ALDH1A1
SCHEMBL7211090 0.66 GAA (0.39) ALDH1A1MAPTMGLL
SCHEMBL12427227 0.66 MGLL (0.32) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064051-A1 Surface active N-halamine compounds AUBURN UNIVERSITY 2003-04-03 US claimed
US-20030044376-A1 Surface active N-halamine compounds AUBURN UNIVERSITY 2003-03-06 US claimed
US-4382765-A TOPICAL COSMETICS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1983-05-10 US claimed
EP-3114164-B1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES INC (US) 2025-07-02 EP disclosed
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 EP disclosed
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2022-03-29 US disclosed
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2020-02-27 US disclosed
EP-3604305-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF Wakunaga Pharmaceutical Co., Ltd. (JP) 2020-02-05 EP disclosed
US-9976055-B2 Lower temperature cure coating compositions KING INDUSTRIES (US) 2018-05-22 US disclosed
US-20150197665-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 US disclosed
US-8729112-B2 Antimicrobial haloalkyl heterocycle compounds NOVABAY PHARMACEUTICALS, INC. (US) 2014-05-20 US disclosed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4469832-A SPRAYABLE COATINGS PPG INDUSTRIES, INC. (US) 1984-09-04 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
US-4447594-A Heat-curable compositions comprising isocyanuric acid-acrolein derivatives MONSANTO COMPANY (US) 1984-05-08 US disclosed
EP-0082832-A2 Radiation and heat curable compositions comprising isocyanuric acid-acrolein derivatives MONSANTO COMPANY (US) 1983-06-29 EP disclosed
US-4382765-A TOPICAL COSMETICS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1983-05-10 US disclosed
US-4314918-A Coating compositions containing organic alcoholic reactive diluents PPG INDUSTRIES, INC. (US) 1982-02-09 US disclosed
US-4042595-A Processes for the production of heterocyclic compounds SNAM PROGETTI S.P.A. (IT) 1977-08-16 US disclosed
US-3959201-A High solids, water thinnable compositions PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044376-A1 Surface active N-halamine compounds AAAS, HNMT, LTN1 KDM4E 2386/4885ALDH1A1 1576/4885MAPT 1508/4885
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF RAB10, HDAC10, NEK10 KDM4E 3143/4885ALDH1A1 207/4885MAPT 4722/4885
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof RARA, RAB10, RABL6 KDM4E 3070/4885ALDH1A1 81/4885MAPT 4766/4885
US-20030064051-A1 Surface active N-halamine compounds AAAS, HNMT, LTN1 KDM4E 2386/4885ALDH1A1 1576/4885MAPT 1508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.