Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valacyclovir SCHEMBL4295083 | 0.86 | KMT2A (0.72) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL34375 | 0.86 | KMT2A (0.72) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL29689659 | 0.85 | HBB (0.72) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL1888797 | 0.84 | KMT2A (0.69) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL19236311 | 0.82 | PDE3A (0.56) | KMT2AMEN1HBBMAPK1PNP | |
| Acyclovir SCHEMBL40723 | 0.80 | PNP (0.67) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL15655101 | 0.78 | MEN1 (0.45) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL4295065 | 0.78 | MEN1 (0.45) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL1477723 | 0.78 | PNP (0.61) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL4295075 | 0.77 | KMT2A (0.48) | KMT2AMEN1HBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209563-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS | SOM INNOVATION BIOTECH, S.A. (ES) | 2021-10-21 | — | — | WO | disclosed |