Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HBB | P68871 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 7/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468669 | 0.83 | PDE3A (0.51) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL4281488 | 0.83 | PDE3A (0.51) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL4295083 | 0.81 | KMT2A (0.72) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL34375 | 0.81 | KMT2A (0.72) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL29689659 | 0.80 | HBB (0.72) | KMT2AMEN1HBBMAPK1PNP | |
| Valacyclovir SCHEMBL1888797 | 0.80 | KMT2A (0.69) | KMT2AMEN1HBBMAPK1PNP | |
| Acyclovir SCHEMBL40723 | 0.78 | PNP (0.67) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL15655101 | 0.78 | MEN1 (0.45) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL4295065 | 0.78 | MEN1 (0.45) | KMT2AMEN1HBBMAPK1PNP | |
| SCHEMBL23948433 | 0.77 | KMT2A (0.53) | KMT2AMEN1HBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200046715-A1 | Medicament for Treating Peripheral Neuropathies | HSIAO LILY (TW) | 2020-02-13 | — | — | US | claimed |
| US-10471064-B2 | Medicament for treating peripheral neuropathies | Hsiao, Lily (TW) | 2019-11-12 | — | — | US | claimed |
| US-20180193348-A1 | Medicament for Treating Peripheral Neuropathies | HSIAO LILY (TW) | 2018-07-12 | — | — | US | claimed |
| US-20170056408-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | YU HSIAO LILY (JP) | 2017-03-02 | — | — | US | claimed |
| US-9549930-B2 | Combined systemic and topical treatment of disordered and/or prodromal stage tissue | QUADEX PHARMACEUTICALS, LLC (US) | 2017-01-24 | — | — | US | claimed |
| US-9545408-B2 | Combined systemic and topical treatment of disordered tissues | QUADEX PHARMACEUTICALS, INC. (US) | 2017-01-17 | — | — | US | claimed |
| US-9526729-B2 | Medicament for treating peripheral neuropathies | Yu, Hsiao Lily (JP) | 2016-12-27 | — | — | US | claimed |
| US-20150238493-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | YU HSIAO LILY (JP) | 2015-08-27 | — | — | US | claimed |
| US-20140213600-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | HSIAO LILY (TW) | 2014-07-31 | — | — | US | claimed |
| US-20230218644-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS | EWHA WOMANS UNIVERSITY (KR) | 2023-07-13 | — | — | US | disclosed |
| US-20220169705-A1 | TOPICAL APPLICATION FOR AN ANTI-HSV ANTIBODY | HEIDELBERG IMMUNOTHERAPEUTICS GMBH (DE) | 2022-06-02 | — | — | US | disclosed |
| US-11267871-B2 | Topical application for an anti-HSV antibody | Heiselberg ImmunoTherapeutics GmbH (DE) | 2022-03-08 | — | — | US | disclosed |
| WO-2021209563-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS | SOM INNOVATION BIOTECH, S.A. (ES) | 2021-10-21 | — | — | WO | disclosed |
| EP-3160997-B1 | TOPICAL APPLICATION FOR AN ANTI-HSV ANTIBODY | HEIDELBERG IMMUNOTHERAPEUTICS GMBH (DE) | 2020-10-28 | — | — | EP | disclosed |
| WO-2014160369-A1 | COMBINED SYSTEMIC AND TOPICAL TREATMENT OF DISORDERED TISSUES | QUADEX PHARMACEUTICALS, LLC (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140274939-A1 | COMBINED SYSTEMIC AND TOPICAL TREATMENT OF DISORDERED TISSUES | QUADEX PHARMACEUTICALS, LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140213600-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | HSIAO LILY (TW) | 2014-07-31 | — | — | US | disclosed |
| US-20140121367-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | PIVOT HOLDING LLC | 2014-05-01 | — | — | US | disclosed |
| WO-2009129094-A2 | COMPOSITIONS CONTAINING ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME | MALLINCKRODT INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| US-20090258843-A1 | Compositions Containing Antiviral Compounds and Methods of Using the Same | MALLINCKRODT INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274939-A1 | COMBINED SYSTEMIC AND TOPICAL TREATMENT OF DISORDERED TISSUES | SAMHD1, DCTD, NT5E | KMT2A 4660/4885MEN1 4618/4885HBB 1441/4885 |
| US-20090258843-A1 | Compositions Containing Antiviral Compounds and Methods of Using the Same | EIF2AK2, MAVS, IRF3 | KMT2A 3346/4885MEN1 3203/4885HBB 3885/4885 |
| US-20140121367-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | TPMT, BHMT2, PFAS | KMT2A 645/4885MEN1 260/4885HBB 2021/4885 |
| US-20230218644-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS | ACE2, ACE, TMPRSS2 | KMT2A 1324/4885MEN1 2508/4885HBB 4552/4885 |
| US-20140213600-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | PMP22, DPM1, SUCLG1 | KMT2A 1711/4885MEN1 632/4885HBB 2084/4885 |
| US-10471064-B2 | Medicament for treating peripheral neuropathies | NGF, TSLP, BDNF | KMT2A 920/4885MEN1 4356/4885HBB 4273/4885 |
| US-20200046715-A1 | Medicament for Treating Peripheral Neuropathies | NGF, PMP22, BPGM | KMT2A 1810/4885MEN1 3466/4885HBB 2477/4885 |
| US-20180193348-A1 | Medicament for Treating Peripheral Neuropathies | NGF, TSLP, BDNF | KMT2A 920/4885MEN1 4356/4885HBB 4273/4885 |
| US-20170056408-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | PMP22, SNCA, PARL | KMT2A 1917/4885MEN1 1309/4885HBB 1450/4885 |
| US-20150238493-A1 | MEDICAMENT FOR TREATING PERIPHERAL NEUROPATHIES | PMP22, SNCA, PARL | KMT2A 1917/4885MEN1 1309/4885HBB 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.