Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 7/20 | 0.41 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29864436 | 0.83 | LMNA (0.60) | TYRO3DYRK1BMEN1LMNAPABPC1 | |
| SCHEMBL2265319 | 0.83 | LMNA (0.60) | TYRO3DYRK1BMEN1LMNAPABPC1 | |
| SCHEMBL1782345 | 0.76 | USP1 (0.43) | TYRO3DYRK1BMEN1LMNAPABPC1 | |
| SCHEMBL23620554 | 0.76 | MEN1 (0.44) | TYRO3DYRK1BMEN1LMNAPABPC1 | |
| SCHEMBL23620499 | 0.73 | JAK2 (0.43) | TYRO3DYRK1BMEN1LMNAPABPC1 | |
| SCHEMBL29501852 | 0.73 | JAK2 (0.43) | TYRO3DYRK1BMEN1LMNAPABPC1 | |
| SCHEMBL24654511 | 0.73 | GSK3B (0.55) | TYRO3DYRK1BMEN1LMNAKMT2A | |
| SCHEMBL18865616 | 0.72 | MTOR (0.51) | LMNAADORA3 | |
| SCHEMBL20359146 | 0.72 | JAK2 (0.54) | — | |
| SCHEMBL23452644 | 0.72 | JAK2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209055-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-10-21 | — | — | WO | disclosed |