Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949002 | 0.92 | TDO2 (0.42) | ACHETDO2CDK5DYRK1ACDK5R1 | |
| SCHEMBL23948946 | 0.91 | GABRA1 (0.41) | TDO2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL23948911 | 0.87 | GABRA1 (0.41) | ACHETDO2GABRA1GABRG2GABRB3 | |
| SCHEMBL23948669 | 0.85 | GABRA1 (0.44) | TDO2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL23948719 | 0.85 | ACHE (0.40) | ACHETDO2CDK5DYRK1ACDK5R1 | |
| SCHEMBL23948668 | 0.84 | ACHE (0.43) | ACHETDO2CDK5DYRK1ACDK5R1 | |
| SCHEMBL23948617 | 0.84 | ACHE (0.43) | ACHETDO2CDK5DYRK1ACDK5R1 | |
| SCHEMBL23948798 | 0.82 | GABRA1 (0.40) | ACHETDO2CDK5DYRK1ACDK5R1 | |
| SCHEMBL23948682 | 0.81 | TDO2 (0.41) | ACHETDO2CDK5DYRK1ACDK5R1 | |
| SCHEMBL23948217 | 0.80 | GABRA1 (0.40) | ACHETDO2CDK5DYRK1ACDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | TEAD4, TEAD2, TEAD1 | ACHE 1059/4885TDO2 224/4885CDK5 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.