SCHEMBL2394920

SCHEMBL2394920

CCn1ccnc1C.Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.48

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAPT P10636 2/20 0.48
HTT P42858 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
LMNA P02545 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GAA P10253 1/20 0.43
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
NOS1 P29475 1/20 0.39
FDPS P14324 1/20 0.39
CYP2D6 P10635 2/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1792059 0.86 ALDH1A1 (0.63) ALDH1A1KDM4ESMN1; SMN2MAPTHTT
SCHEMBL30564825 0.86 ALDH1A1 (0.47) ALDH1A1KDM4ESMN1; SMN2MAPTHTT
SCHEMBL29860030 0.85 ALDH1A1 (0.45) ALDH1A1KDM4ESMN1; SMN2MAPTHTT
Sulfuric Acid SCHEMBL28294807 0.84 KMT2A (0.52) ALDH1A1LMNAL3MBTL1KMT2APOLB
Sulfuric Acid SCHEMBL28650399 0.84 KMT2A (0.52) ALDH1A1LMNAL3MBTL1KMT2APOLB
SCHEMBL21173942 0.82 KMT2A (0.50) ALDH1A1LMNAL3MBTL1KMT2APOLB
SCHEMBL28831716 0.81 ALDH1A1 (0.42) ALDH1A1KDM4ESMN1; SMN2MAPTHTT
SCHEMBL3415553 0.80 S1PR3 (0.44) ALDH1A1KDM4ESMN1; SMN2HTTLMNA
SCHEMBL2998201 0.80 KDM4E (0.51) ALDH1A1KDM4ESMN1; SMN2MAPTHTT
Trifluoromethanesulfonic Acid SCHEMBL1681813 0.78 FDPS (0.46) ALDH1A1KDM4ETDP1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO disclosed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
US-8027150-B2 Conductive polymer solid electrolytic capacitor KANEKA CORPORATION (JP) 2011-09-27 US disclosed
US-20080218942-A1 Conductive polymer solid electrolytic capacitor KANEKA CORPORATION (JP) 2008-09-11 US disclosed